Article
Midline invasion predicts poor prognosis in diffuse hemispheric glioma, H3 G34-mutant: an individual participant data review.
Journal of neuro-oncology - 1 Mar 2024
Kegoya Yasuhito, Otani Yoshihiro, Inoue Yohei, Mizuta Ryo, Higaki Fumiyo, Washio Kana, Koizumi Shinichiro, Kurozumi Kazuhiko, Ishida Joji, Fujii Kentaro, Yamamoto Norio, Tanaka Yoshihiro, Date Isao
Abstract excerpt
INTRODUCTION: Diffuse hemispheric glioma, H3 G34-mutant (DHGs), is a newly categorized tumor in pediatric-type diffuse high-grade gliomas, World Health Organization grade 4, with a poor prognosis. Although prognostic factors associated with genetic abnormalities have been reported, few reports have examined the clinical presentation of DHGs, especially from the viewpoint of imaging findings. In this study, we...
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