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Article

Genetic risk of chronic pain conditions associated with risk of suicide death through an integrative analysis of EHR and genomics data.

Translational psychiatry - 16 Feb 2026

Han Seonggyun, DiBlasi Emily, Monson Eric T, Shabalin Andrey A, Baird Lisa, Chen Danli, Lamichhane Dirga, Tharp Doug, Ferris Elliott, Yu Zhe, Brandon Callor W, Staley Michael J, Li Qingqin S, Willour Virginia, Crockett David K, Eilbeck Karen, Bakian Amanda V, Keeshin Brooks R, Okifuji Akiko, Coon Hilary, Docherty Anna R

Abstract excerpt

Chronic pain represents heritable conditions linked to suicide death. It has been suggested that a shared genetic predisposition may contribute to this relationship, but there has not yet been a comprehensive assessment of genetic and clinical overlaps of different types of chronic pain with suicide death. Here, we integrated whole-genome sequencing and electronic health records from 986 unrelated individuals of...

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Identifiers

PMID: 41698884
DOI: 10.1038/s41398-026-03861-6
PMCID: PMC12949045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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