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Article

A novel method for analyzing genetic association with longitudinal phenotypes.

Statistical applications in genetics and molecular biology - 13 Mar 2013

Londono Douglas, Chen Kuo-mei, Musolf Anthony, Wang Ruixue, Shen Tong, Brandon January, Herring John A, Wise Carol A, Zou Hong, Jin Meilei, Yu Lei, Finch Stephen J, Matise Tara C, Gordon Derek

Abstract excerpt

Knowledge of genes influencing longitudinal patterns may offer information about predicting disease progression. We developed a systematic procedure for testing association between SNP genotypes and longitudinal phenotypes. We evaluated false positive rates and statistical power to localize genes for disease progression. We used genome-wide SNP data from the Framingham Heart Study. With longitudinal data from two...

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Identifiers

PMID: 23502345
DOI: 10.1515/sagmb-2012-0070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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