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Article

Concordance between genomic alterations assessed by next-generation sequencing in tumor tissue or circulating cell-free DNA.

Oncotarget - 4 Oct 2016

Chae Young Kwang, Davis Andrew A, Carneiro Benedito A, Chandra Sunandana, Mohindra Nisha, Kalyan Aparna, Kaplan Jason, Matsangou Maria, Pai Sachin, Costa Ricardo, Jovanovic Borko, Cristofanilli Massimo, Platanias Leonidas C, Giles Francis J

Abstract excerpt

Genomic analysis of tumor tissue is the standard technique for identifying DNA alterations in malignancies. Genomic analysis of circulating tumor cell-free DNA (cfDNA) represents a relatively non-invasive method of assessing genomic alterations using peripheral blood. We compared the concordance of genomic alterations between cfDNA and tissue biopsies in this retrospective study. Twenty-eight patients with...

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PMID: 27588476
DOI: 10.18632/oncotarget.11692
PMCID: PMC5323161

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APC
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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