Article
Clinical implications of plasma circulating tumor DNA in gynecologic cancer patients.
Molecular oncology - 1 Jan 2021
Charo Lindsey M, Eskander Ramez N, Okamura Ryosuke, Patel Sandip P, Nikanjam Mina, Lanman Richard B, Piccioni David E, Kato Shumei, McHale Michael T, Kurzrock Razelle
Abstract excerpt
Molecular characterization of cancers is important in dictating prognostic factors and directing therapy. Next-generation sequencing of plasma circulating tumor DNA (ctDNA) offers less invasive, more convenient collection, and a more real-time representation of a tumor and its molecular heterogeneity than tissue. However, little is known about the clinical implications of ctDNA assessment in gynecologic cancer....
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