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Article

Highly sensitive profiling somatic mutations of thyroid cancer by nucleotide-enrichment-based MALDI-TOF MS assay.

Scientific reports - 10 Feb 2026

Bai Huili, Li Ying, Li Jia, Liu Ting, Xiao Jun, Xia Lihui, Sun Xueqin, Cheng Wei

Abstract excerpt

Multiple mutation detection is increasingly essential for clinical applications targeting the diagnosis, treatment decision-making, and prognosis assessment of thyroid cancer, especially for the limited amount of thyroid fine-needle aspiration (FNA) samples. However, there is a lack of cost-effective methods that can simultaneously achieve high sensitivity and high throughput for thyroid cancer. Herein, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41667808
DOI: 10.1038/s41598-026-39755-2
PMCID: PMC12960701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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