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Article

Development and Analytical Validation of an Expanded Mutation Detection Panel for Next-Generation Sequencing of Thyroid Nodule Aspirates.

The Journal of molecular diagnostics : JMD - 1 Mar 2020

Ablordeppey Kenny K, Timmaraju Venkata A, Song-Yang Joanna W, Yaqoob Sharon, Narick Christina, Mireskandari Alidad, Finkelstein Sydney D, Kumar Gyanendra

Abstract excerpt

Molecular analysis is used to evaluate the risk of malignancy for thyroid fine-needle aspirates, identified as indeterminate by microscopic cytology, on the basis of the detection of various oncogenic DNA mutations and fusion transcripts or on the use of various mRNAs or miRNA-based classifier algorithms. Our approach has been to use a combination test using the detection of oncogenic mutations/fusion transcripts...

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Share to Amino Acid Substitution
Share to Biopsy, Fine-Needle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

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Source

Identifiers

PMID: 31866571
DOI: 10.1016/j.jmoldx.2019.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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