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Article

Investigating the phenotypic alterations associated with hypermucoviscous hypervirulent Klebsiella pneumoniae during phage resistance development.

BMC microbiology - 22 Aug 2025

Juliet Ramya, Nachimuthu Ramesh

Abstract excerpt

Phage therapy has been explored and used compassionately in the post-antibiotic era, though phage resistance might pose a serious challenge. The advent of hypervirulent and hypermucoviscous traits in Klebsiella pneumoniae limits therapeutic choices. This study investigated the phage resistance in hypermucoviscous hypervirulent Klebsiella pneumoniae clinical strain Kleb_53. A Klebsiella phage Disc against the...

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Identifiers

PMID: 40841996
DOI: 10.1186/s12866-025-04268-x
PMCID: PMC12372256

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