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Article

Precision oncology in Bulgaria: a prospective study of metastatic colorectal cancer patients.

Cancer treatment and research communications - 1 Jan 2026

Dimitrov George, Kamburova Zornitsa, Petrov Krassimir, Dimitrov Dobromir, Popovska Savelina

Abstract excerpt

BACKGROUND: Geographic disparities in access to molecular diagnostics and targeted therapies affect the implementation of precision oncology in metastatic colorectal cancer (mCRC), particularly in Eastern Europe. This prospective study aimed to characterize the molecular landscape of advanced CRC in Bulgarian patients and evaluate associations between genomic alterations, mismatch repair (MMR) status, and stromal...

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Source

Identifiers

PMID: 41653877
DOI: 10.1016/j.ctarc.2026.101128

Genes

KRAS
AKT1
EGFR
ERBB2
NRAS
PIK3CA
RET
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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