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Article

Mismatch repair deficiency assessment by immunohistochemistry: for Lynch syndrome screening and beyond.

Future oncology (London, England) - 1 Nov 2018

Wong Hui-Li, Christie Michael, Gately Lucy, Tie Jeanne, Lee Belinda, Semira Christine, Lok Sheau Wen, Wong Rachel, Gibbs Peter

Abstract excerpt

While mismatch repair (MMR) deficiency has been studied extensively, the assessment of MMR status in colorectal and other cancers remains highly relevant, particularly in light of recent data demonstrating that MMR deficiency is a strong predictor for treatment benefit with immune checkpoint inhibitors across multiple tumor types. In colorectal cancer, there is a growing consensus in support of routine MMR...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 30004261
DOI: 10.2217/fon-2018-0319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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