Article
Causal effect of chloride intracellular channel protein 5 on chronic periodontitis: A Mendelian randomization study.
Medicine - 6 Feb 2026
Hui Jifang, Gao Yunan, Liang Wenhui, Liu Jingjing, Luo Ping, Qi Bing, Qiao Hu
Abstract excerpt
This study aimed to evaluate the potential causal effect of chloride intracellular channel protein 5 (CLIC5) on the risk of chronic periodontitis (CP) using a Mendelian randomization (MR) approach. MR analysis was conducted utilizing publicly available summary statistics from genome-wide association studies summary statistics for CLIC5 and CP. Multiple MR methods, including inverse variance weighted, MR Egger,...
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