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Article

Causal effect between chronic periodontitis and IgA nephropathy: Insights from a 2-sample bidirectional Mendelian randomization study.

Medicine - 19 Jun 2026

Miao He, Guan Feifei, Huang Jiaguo, Hua Runmiao

Abstract excerpt

Epidemiological evidence suggests an association between chronic periodontitis and immunoglobulin A nephropathy (IgAN), although this association remains controversial. This study aimed to investigate the causal effect between chronic periodontitis and IgAN using a 2-sample bidirectional Mendelian randomization (MR) analysis, using single nucleotide polymorphisms as genetic instrumental variables obtained from...

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Share to Chronic Periodontitis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Glomerulonephritis, IGA

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 42332522
DOI: 10.1097/MD.0000000000049419
PMCID: PMC13286464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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