Article
Prediction of eye and hair pigmentation phenotypes using the HIrisPlex system in a Brazilian admixed population sample.
International journal of legal medicine - 1 Jul 2021
Carratto Thássia Mayra Telles, Marcorin Letícia, do Valle-Silva Guilherme, de Oliveira Maria Luiza Guimarães, Donadi Eduardo Antônio, Simões Aguinaldo Luiz, Castelli Erick C, Mendes-Junior Celso Teixeira
Abstract excerpt
Human pigmentation is a complex trait, probably involving more than 100 genes. Predicting phenotypes using SNPs present in those genes is important for forensic purpose. For this, the HIrisPlex tool was developed for eye and hair color prediction, with both models achieving high accuracy among Europeans. Its evaluation in admixed populations is important, since they present a higher frequency of intermediate...
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