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Clinicopathologic and Molecular Features of Tubo-Ovarian Carcinosarcomas With an Emphasis on p53 Wild-Type, KRAS-Mutated Tumors.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2026

Hammer Phoebe M, Kingsley Leandra G, Sasse Simone A, Howitt Brooke E

Abstract excerpt

Tubo-ovarian carcinosarcomas (OCS) are uncommon, aggressive tumors. Recent literature in uterine carcinosarcomas has shown prognostic differences by the molecular classification established by The Cancer Genome Atlas. Our aim was to delineate the molecular subtypes within OCS and associated clinicopathologic, immunohistochemical, and additional molecular features. A total of 57 OCS were identified at our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41638575
DOI: 10.1016/j.modpat.2026.100971

Genes

KRAS
POLE
WT1

Provenance

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