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Not all uterine carcinosarcomas are created equal: Survival outcomes according to molecular characterization of uterine carcinosarcoma.

Gynecologic oncology - 1 Feb 2025

Toboni Michael D, Dinkins Kaitlyn, Wu Sharon, Mattox Tyler, Oberley Matthew J, Thaker Premal H, Herzog Thomas J, Powell Matthew A, Jones Nathaniel

Abstract excerpt

OBJECTIVES: To assess if ProMisE classifier molecular subtypes are associated with differing survival outcomes in uterine carcinosarcoma (UCS) and compare these outcomes to endometrioid endometrial cancer (EEC) tumors. METHODS: There were 2235 UCS and 6469 EEC tumors using next-generation sequencing of DNA, whole exome sequencing, and RNA. Microsatellite instability (MSI) was tested by IHC and NGS. Real-world...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39837013
DOI: 10.1016/j.ygyno.2024.12.012

Genes

POLE
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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