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What is the best approach to blood transfusion in sickle cell disease? A scientometric analysis and literature review.

Transfusion medicine (Oxford, England) - 1 Jun 2026

Carminati Christiane Ruffato, Ananias Lucas Fernandes, da Silva Saulo Fernando Moreira, Carneiro Anna Cecília Dias Maciel, de Souza Helio Moraes, Tanaka Sarah Cristina Sato Vaz, De Vito Fernanda Bernadelli

Abstract excerpt

BACKGROUND: Blood transfusion remains a cornerstone in the management of sickle cell disease (SCD); however, it is frequently complicated by red cell alloimmunisation. A significant debate persists within the scientific community regarding the optimal strategy to mitigate this risk: the traditional, pragmatic approach of serologic phenotyping versus molecular genotyping, which is technically superior yet more...

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PMID: 41631680
DOI: 10.1111/tme.70064

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SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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