Article
Genotyping and the Future of Transfusion in Sickle Cell Disease.
Hematology/oncology clinics of North America - 1 Dec 2022
Karafin Matthew S, Howard Jo
Abstract excerpt
Patients with sickle cell disease (SCD) have a high rate of red cell alloimmunization, which increases morbidity and mortality. Reasons for this susceptibility are multifactorial, but differences in antigen frequency between donors and recipients are one of the modifiable risk factors. Here, we evaluate the benefits of red cell molecular antigen-typing for both patients with SCD and their donors and describe how...
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