Clinical and genetic ancestry profile of a large multi-centre sickle cell disease cohort in Brazil.

doi:10.1111/bjh.15462

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Clinical and genetic ancestry profile of a large multi-centre sickle cell disease cohort in Brazil.

British journal of haematology - 1 Sept 2018

Carneiro-Proietti Anna B F, Kelly Shannon, Miranda Teixeira Carolina, Sabino Ester C, Alencar Cecilia S, Capuani Ligia, Salomon Silva Tassila P, Araujo Aderson, Loureiro Paula, Máximo Cláudia, Lobo Clarisse, Flor-Park Miriam V, Rodrigues Daniela O W, Mota Rosimere A, Gonçalez Thelma T, Hoppe Carolyn, Ferreira João E, Ozahata Mina, Page Grier P, Guo Yuelong, Preiss Liliana R, Brambilla Donald, Busch Michael P, Custer Brian

Abstract excerpt

Approximately 3500 children with sickle cell disease (SCD) are born in Brazil each year, but the burden of SCD morbidity is not fully characterised. A large, multi-centre cohort was established to characterise clinical outcomes in the Brazilian SCD population and create the infrastructure to perform genotype-phenotype association studies. Eligible patients were randomly selected from participating sites and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Sickle Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brazil

Share to Child, Preschool

Share to Cohort Studies

Share to Genetic Association Studies

Share to Genome-Wide Association Study

Share to Hemoglobin, Sickle

Share to Pedigree

Source

Open in PubMed Open full text

Identifiers

PMID: 30027669
DOI: 10.1111/bjh.15462
PMCID: PMC8019534

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical and genetic ancestry profile of a large multi-centre sickle cell disease cohort in Brazil.PMID 30027669Read ↗

Comparative study of sickle cell anemia and hemoglobin SC disease: clinical characterization, laboratory biomarkers and genetic profilesSemantic proximity Read ↗

Genetic Variation and Sickle Cell Disease Severity: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

An Analysis of Racial and Ethnic Backgrounds Within the CASiRe International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Research.Semantic proximity Read ↗

Potential Association of Sickle Cell Disease Genotypes (Ss, as, Sβ Thalassemia) With Abo Blood Groups: In Indian PopulationSemantic proximity Read ↗

Genetic patterns & public health implications of sickle cell anaemia across populations: A systematic review.Semantic proximity Read ↗

Updated Worldwide Epidemiology of Inherited Erythrocyte DisordersSemantic proximity Read ↗

Epidemiology of sickle cell disease in Saudi Arabia.Semantic proximity Read ↗

The phenotypes of sickle cell disease: strategies to aid the identification of undiagnosed patients in the Italian landscapeSemantic proximity Read ↗

Sickle Cell Clinical Research and Intervention Program (SCCRIP): A lifespan cohort study for sickle cell disease progression from the pediatric stage into adulthood.Semantic proximity Read ↗

Utilizing Whole-Exome Sequencing to Characterize the Phenotypic Variability of Sickle Cell Disease.Semantic proximity Read ↗

Genomic ancestry evaluated by ancestry-informative markers in patients with sickle cell disease.Semantic proximity Read ↗

Sickle cell disease: A distinction of two most frequent genotypes (HbSS and HbSC).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.