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Identification and validation of oxidative stress and immune-related hub genes in Alzheimer’s disease through bioinformatics analysis

12 Jan 2023

Abstract excerpt

Alzheimer's disease (AD) is the leading cause of dementia in aged population. Oxidative stress and neuroinflammation play important roles in the pathogenesis of AD. Investigation of hub genes for the development of potential therapeutic targets and candidate biomarkers is warranted. The differentially expressed genes (DEGs) in AD were screened in GSE48350 dataset. The differentially expressed oxidative stress...

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PMID: 36635346
DOI: 10.1038/s41598-023-27977-7

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