Article
Limited evidence for transgenerational chromosomal instability in families with elevated mutation pattern SBS16 in the germline.
International journal of radiation biology - 1 Jan 2026
Stephens Jade, Ermler Sibylle, Rake Christine, Sisu Cristina, Scholze Martin, Anderson Rhona M
Abstract excerpt
PURPOSE: The transgenerational effects of preconception parental radiation exposure in humans remain unclear. We assessed genomic integrity in adult children of British nuclear test (NT) veterans-a community that has expressed long-standing concerns about adverse health effects, including in their offspring-to investigate for any constitutional chromosomal abnormalities and/or cytogenetic indicators of genomic...
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