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Article

Immortalization and Targeted Enrichment of HIV-Infected CD4+ T-Cells from Patients Under Antiretroviral Therapy.

International journal of molecular sciences - 22 Jan 2026

Bruchey Whitney E, Paudel Sharada, McCormack Ashley L, Imamichi Tomozumi, Laverdure Sylvain

Abstract excerpt

Defective HIV-1 proviruses harboring mutations and/or large internal deletions represent the majority of HIV-1 sequences found in circulating peripheral blood mononuclear cells of people living with HIV with viremia suppressed by combination antiretroviral therapy; indirect evidence suggests that such sequences are transcriptionally active and may contribute to immune activation. In this study, we present a new...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41596728
DOI: 10.3390/ijms27021086
PMCID: PMC12841691

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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