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Article

Genome-wide association and integrative analyses of relative handgrip strength identify polygenic determinants of gastrointestinal disorder susceptibility.

BMC gastroenterology - 27 Jan 2026

Jiang Pan, Fang Yanfei, Liu Zhengye, Du Hanze, Bai Xiaoyin, Chen Haotian, Mi Jiarui

Abstract excerpt

BACKGROUND: Hand grip strength is a crucial indicator of muscle strength and quality. Yet, there remain significant knowledge gaps in our understanding of the genetic factors that influence hand grip strength and its impact on digestive disorders. METHODS: This study employed data from the UK Biobank, comprising 405,394 individuals of European ancestry, who underwent assessments of both left- and right- hand grip...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41593506
DOI: 10.1186/s12876-026-04624-9
PMCID: PMC12918038

Genes

CEP192
L3MBTL3
NUCKS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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