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A GWAS for grip strength in cohorts of children-Advantages of analysing young participants for this trait.

Genes, brain, and behavior - 1 Oct 2024

Abbondanza Filippo, Wang Carol A, Schmitz Judith, Marianski Krzysztof, Pennell Craig E, Whitehouse Andrew J O, Paracchini Silvia

Abstract excerpt

Grip strength (GS) is a proxy measure for muscular strength and a predictor for bone fracture risk among other diseases. Previous genome-wide association studies (GWASs) have been conducted in large cohorts of adults focusing on scores collected for the dominant hand, therefore increasing the likelihood of confounding effects by environmental factors. Here, we perform the first GWAS meta-analyses on maximal GS...

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Adolescent
Child
Cohort Studies
Genome-Wide Association Study
Hand Strength

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Quantitative Trait Loci

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Open in PubMed Open full text

Identifiers

PMID: 39377282
DOI: 10.1111/gbb.70003
PMCID: PMC11459231

Genes

HOXB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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