Article
Lifestyle factors, genetic susceptibility and risk of incident diverticulitis: an integrated analysis of four prospective cohort studies and electronic health records-linked biobank.
Gut - 10 Nov 2025
Ma Wenjie, Ha Jane, Neylan Christopher J, Munro Heather, Skerrett Duncan, Downie Jonathan M, Sevilla-González Magdalena, Steinwandel Mark, Mumma Michael, Zheng Wei, Maguire Lillias H, Giovannucci Edward L, Strate Lisa L, Chan Andrew T
Abstract excerpt
BACKGROUND: Both lifestyle factors and genetic predisposition contribute to the development of diverticulitis. OBJECTIVE: To examine whether lifestyle modification can reduce the genetic risk of diverticulitis. DESIGN: We derived an overall healthy lifestyle score for diverticulitis based on smoking, body mass index (BMI), physical activity, fibre and red meat among 179 564 participants in three prospective...
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