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Article

Host genetic variation and gut microbiome in pediatric diseases.

Chinese medical journal - 20 Mar 2026

Meng Yi, Wang Hua, Mu Dezhi, Zeng Shuqin, Wang Shaopu

Abstract excerpt

ABSTRACT: Pediatric health is the foundation for people's lifelong health. The co-evolution of host genetics and the gut microbiome fosters a symbiotic relationship that is important for pediatric growth and the pathogenesis of various diseases. However, a comprehensive overview of the human genetics-gut microbiome axis in pediatric diseases remains unavailable. This review summarizes the human genetic variants...

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PMID: 41588607
DOI: 10.1097/CM9.0000000000003959
PMCID: PMC12999166

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