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Article

Interactions between host genetics and gut microbiome influence susceptibility to childhood asthma and lung function.

The Journal of allergy and clinical immunology - 1 Apr 2026

Miyachi Hideaki, Shibata Ryohei, Javornik Cregeen Sara J, Surathu Anil, Sijaric Maida, Espinola Janice A, Sullivan Ashley F, Mansbach Jonathan M, Camargo Carlos A, Zhu Zhaozhong

Abstract excerpt

BACKGROUND: The gut microbiome is thought to influence risk of childhood allergic diseases; however, the data on species-level links to childhood asthma and lung function are limited, and the role of host genetics in the gut-lung axis remains unclear. METHODS: In a multicenter cross-sectional study of children with a history of bronchiolitis from the 35th Multicenter Airway Research Collaboration, we performed...

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Identifiers

PMID: 41485494
DOI: 10.1016/j.jaci.2025.12.1005
PMCID: PMC13135221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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