Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Putative azithromycin resistance mutations in Chlamydia trachomatis are globally distributed but arose before azithromycin was discovered.

Antimicrobial agents and chemotherapy - 4 Mar 2026

Sharma Parul, Dean Deborah, Read Timothy D

Abstract excerpt

Azithromycin is widely used to treat Chlamydia trachomatis infections, yet the extent of resistance to the drug across the species has not been addressed. We surveyed mutations and substitutions linked to putative azithromycin resistance across 1,349 high-quality C. trachomatis genomes. Mutations in the rplV gene encoding three non-synonymous substitutions, compared with the canonical C. trachomatis reference...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Azithromycin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chlamydia Infections

Share to Chlamydia trachomatis

Share to Drug Resistance, Bacterial

Share to Microbial Sensitivity Tests

Share to Phylogeny

Share to RNA, Ribosomal, 23S

Source

Open in PubMed Open full text

Identifiers

PMID: 41586501
DOI: 10.1128/aac.01708-25
PMCID: PMC12959087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Putative azithromycin resistance mutations in Chlamydia trachomatis are globally distributed but arose before azithromycin was discovered.PMID 41586501Read ↗

Putative azithromycin-resistance mutations in <i>Chlamydia trachomatis</i> are globally distributed but arose before azithromycin was discoveredSemantic proximity Read ↗

Azithromycin susceptibility of Neisseria gonorrhoeae in the USA in 2017: a genomic analysis of surveillance dataSemantic proximity Read ↗

Genomic Epidemiology and Molecular Resistance Mechanisms of Azithromycin-Resistant Neisseria gonorrhoeae in Canada from 1997 to 2014.Semantic proximity Read ↗

Emergence of High-Level Azithromycin Resistance in Neisseria gonorrhoeae : Genomic Insights From a 9-Year (2016-2024) Study From North India.Semantic proximity Read ↗

The Synergistic Armory: A Global Genome-Wide Association Study Reveals the Integrated Mechanisms of Azithromycin Resistance in Neisseria gonorrhoeae.Semantic proximity Read ↗

WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014.Semantic proximity Read ↗

Molecular epidemiology and mechanisms of resistance of azithromycin-resistant Neisseria gonorrhoeae isolated in France during 2013-14.Semantic proximity Read ↗

Genomic Characterization of Neisseria gonorrhoeae Strains from 2016 U.S. Sentinel Surveillance Displaying Reduced Susceptibility to Azithromycin.Semantic proximity Read ↗

Molecular mechanisms of Chlamydia trachomatis resistance to antimicrobial drugs.Semantic proximity Read ↗

Atypical Mutation in Neisseria gonorrhoeae 23S rRNA Associated with High-Level Azithromycin Resistance.Semantic proximity Read ↗

Chlamydia trachomatis clinical isolates identified as tetracycline resistant do not exhibit resistance in vitro: whole-genome sequencing reveals a mutation in porB but no evidence for tetracycline resistance genes.Semantic proximity Read ↗

Local emergence and global evolution of Neisseria gonorrhoeae with high-level resistance to azithromycin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.