Article
Circulating metabolites mediating the effect of psoriatic arthritis on Crohn disease risk: A mediation Mendelian randomization study.
Medicine - 23 Jan 2026
Qin Xia, Deng Junyang, Chen Bocheng, Tan Xi, Xie Xiaoting, Zhou Guiyou, Hou Wei, Wen Sijian, Lin Youkun
Abstract excerpt
Psoriatic arthritis (PsA) and Crohn disease (CD) are chronic immune-mediated illnesses that afflict a growing number of adults and children worldwide. Observational studies have revealed a link between PsA and CD, but the modifiable risk variables that mediate the causal effects remain unknown. We aim to look into the relationship between PsA and CD, and to see if circulating metabolites have a role in the...
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