Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fanconi anemia complementation group C gene (FANCC) association with hereditary and sporadic renal tumors.

The oncologist - 5 Feb 2026

Desai Devashish, Sager Rebecca A, Basin Michael, Jacob Joseph M, Morris Gloria Joan, Spiess Philippe E, Li Roger, Cheng Liang, Necchi Andrea, Kamat Ashish M, Grivas Petros, Pavlick Dean, Goldberg Hanan, Mollapour Mehdi, Lin Douglas, Ross Jeffrey S, Bratslavsky Gennady, Basnet Alina, Daneshvar Michael A

Abstract excerpt

BACKGROUND: Inactivating genomic alterations (GA) of the FANCC gene are associated with genomic instability, DNA cross-linking, and homologous DNA repair deficiency. Here, we evaluated the incidence of FANCC GA in renal tumors (RT). METHODS: A total of 463 546 clinically advanced cancer (CAC) cases underwent hybrid capture-based comprehensive genomic profiling using the FDA-approved F1CDx assay to detect all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to FANCC gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Neoplasms

Share to Microsatellite Instability

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 41557860
DOI: 10.1093/oncolo/oyag012
PMCID: PMC12923112

Genes

FANCC
SUSD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fanconi anemia complementation group C gene (FANCC) association with hereditary and sporadic renal tumors.PMID 41557860Read ↗

Hereditary Renal Cancer Syndromes: Clinicopathologic Features and Correlation With Tumors Harboring Somatic Mutations.Semantic proximity Read ↗

Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma.Semantic proximity Read ↗

Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma.Semantic proximity Read ↗

Referral patterns and genetic testing outcomes in a contemporary hereditary renal cancer clinic.Semantic proximity Read ↗

Prevalence and Landscape of Actionable Genomic Alterations in Renal Cell Carcinoma.Semantic proximity Read ↗

Germline Mutation Landscape and Associated Clinical Characteristics in Chinese Patients With Renal Cell CarcinomaSemantic proximity Read ↗

Characterization of Clinical Cases of Advanced Papillary Renal Cell Carcinoma via Comprehensive Genomic Profiling.Semantic proximity Read ↗

Renal tumors harboring FLCN mutations: Case series from clinical practice.Semantic proximity Read ↗

Genome-Wide Uniparental Disomy and Copy Number Variations in Renal Cell Carcinomas Associated with Birt-Hogg-Dubé Syndrome.Semantic proximity Read ↗

Candidate variants in DNA replication and repair genes in early-onset renal cell carcinoma patients referred for germline testing.Semantic proximity Read ↗

Germline mutations of renal cancer predisposition genes and clinical relevance in Chinese patients with sporadic, early‐onset diseaseSemantic proximity Read ↗

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.