Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-Wide Uniparental Disomy and Copy Number Variations in Renal Cell Carcinomas Associated with Birt-Hogg-Dubé Syndrome.

The American journal of pathology - 1 Feb 2016

Iribe Yasuhiro, Yao Masahiro, Tanaka Reiko, Kuroda Naoto, Nagashima Yoji, Nakatani Yukio, Furuya Mitsuko

Abstract excerpt

Birt-Hogg-Dubé syndrome is an inherited disorder caused by germline mutations of the folliculin gene (FLCN). The affected patients are prone to developing renal cell carcinomas (RCCs). Most mutant FLCN-associated RCCs (mFLCN-RCCs) are histologically chromophobe RCCs and hybrid oncocytic/chromophobe tumors. It is incompletely understood whether mFLCN-RCCs have different chromosomal abnormalities compared with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birt-Hogg-Dube Syndrome
Share to Carcinoma, Renal Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human

Share to DNA Copy Number Variations

Share to Kidney Neoplasms

Share to Proto-Oncogene Proteins

Share to Tumor Suppressor Proteins

Share to Uniparental Disomy

Source

Identifiers

PMID: 26776076
DOI: 10.1016/j.ajpath.2015.10.013

Genes

FLCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Uniparental Disomy and Copy Number Variations in Renal Cell Carcinomas Associated with Birt-Hogg-Dubé Syndrome.PMID 26776076Read ↗

Clinical genomics of renal epithelial tumors.Semantic proximity Read ↗

Comparative analyses define differences between BHD-associated renal tumour and sporadic chromophobe renal cell carcinomaSemantic proximity Read ↗

Distinctive expression patterns of glycoprotein non-metastatic B and folliculin in renal tumors in patients with Birt-Hogg-Dubé syndrome.Semantic proximity Read ↗

Birt-Hogg-Dubé renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expressionSemantic proximity Read ↗

Immunohistochemical characterization of renal tumors in patients with Birt-Hogg-Dubé syndrome.Semantic proximity Read ↗

Renal tumors harboring FLCN mutations: Case series from clinical practice.Semantic proximity Read ↗

Review of renal tumors associated with Birt-Hogg-Dubé syndrome with focus on clinical and pathobiological aspects.Semantic proximity Read ↗

A novel missense mutation in the folliculin gene associated with the renal tumor-only phenotype of Birt-Hogg-Dubé syndrome.Semantic proximity Read ↗

Birt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome.Semantic proximity Read ↗

Birt‐Hogg‐Dubé syndrome‐associated renal cell carcinoma: Histopathological features and diagnostic conundrumSemantic proximity Read ↗

Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.Semantic proximity Read ↗

Heterozygous germline FLCN mutation in Birt-Hogg-Dubé syndrome with bilateral renal hybrid oncocytic/chromophobe tumor and unilateral renal chromophobe cell carcinoma: a case report.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.