Prevalence and Landscape of Actionable Genomic Alterations in Renal Cell Carcinoma.

doi:10.1158/1078-0432.CCR-20-4058

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Prevalence and Landscape of Actionable Genomic Alterations in Renal Cell Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2021

Attalla Kyrollis, DiNatale Renzo G, Rappold Phillip M, Fong Christopher J, Sanchez-Vega Francisco, Silagy Andrew W, Weng Stanley, Coleman Jonathan, Lee Chung-Han, Carlo Maria I, Durack Jeremy C, Solomon Stephen B, Reuter Victor E, Russo Paul, Chan Timothy A, Motzer Robert J, Schultz Nikolaus D, Reznik Ed, Voss Martin H, Hakimi A Ari

Abstract excerpt

PURPOSE: We report our experience with next-generation sequencing to characterize the landscape of actionable genomic alterations in renal cell carcinoma (RCC). EXPERIMENTAL DESIGN: A query of our institutional clinical sequencing database (MSK-IMPACT) was performed that included tumor samples from 38,468 individuals across all cancer types. Somatic variations were annotated using a precision knowledge database...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Renal Cell

Share to Ferroptosis and cancer prognosis

Share to Genome

Share to High-Throughput Nucleotide Sequencing

Share to Kidney Neoplasms

Share to Mutation

Share to Renal cell carcinoma treatment

Source

Open in PubMed Open full text

Identifiers

PMID: 34261695
DOI: 10.1158/1078-0432.CCR-20-4058
PMCID: PMC8530915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence and Landscape of Actionable Genomic Alterations in Renal Cell Carcinoma.PMID 34261695Read ↗

Actionable genomic landscapes from a real-world cohort of urothelial carcinoma patients.Semantic proximity Read ↗

Renal cell carcinoma deep sequencing: recent developments.Semantic proximity Read ↗

The Landscape of Whole-genome Alterations and Pathologic Features in Genitourinary Malignancies: An Analysis of the Cancer Genome Atlas.Semantic proximity Read ↗

Correlation of genomic alterations assessed by next-generation sequencing (NGS) of tumor tissue DNA and circulating tumor DNA (ctDNA) in metastatic renal cell carcinoma (mRCC): potential clinical implications.Semantic proximity Read ↗

Prevalence and co-occurrence of actionable genomic alterations in high-grade bladder cancer.Semantic proximity Read ↗

Clinical next generation sequencing to identify actionable aberrations in a phase I program.Semantic proximity Read ↗

SnapShot: Renal Cell Carcinoma.Semantic proximity Read ↗

Concurrent tissue and circulating tumor DNA analysis in renal cell carcinoma: insights from a multimodal database.Semantic proximity Read ↗

Germline Mutation Landscape and Associated Clinical Characteristics in Chinese Patients With Renal Cell CarcinomaSemantic proximity Read ↗

Characterization of Clinical Cases of Advanced Papillary Renal Cell Carcinoma via Comprehensive Genomic Profiling.Semantic proximity Read ↗

Wide spetcrum mutational analysis of metastatic renal cell cancer: a retrospective next generation sequencing approach.Semantic proximity Read ↗

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.