Article
Both the subtypes of KIT mutation and minimal residual disease are associated with prognosis in core binding factor acute myeloid leukemia: a retrospective clinical cohort study in single center.
Annals of hematology - 1 May 2021
Duan Wenbing, Liu Xiaohong, Zhao Xiaosu, Jia Jinsong, Wang Jing, Gong Lizhong, Jiang Qian, Zhao Ting, Wang Yu, Zhang Xiaohui, Xu Lanping, Shi Hongxia, Chang Yingjun, Liu Kaiyan, Huang Xiaojun, Qin Yazhen, Jiang Hao
Abstract excerpt
Core binding factor acute myeloid leukemia (CBF-AML), including cases with KIT mutation, is currently defined as a low-risk AML. However, some patients have poor response to treatment, and the prognostic significance of KIT mutation is still controversial. This study aimed to explore the prognostic significance of different KIT mutation subtypes and minimal residual disease (MRD) in CBF-AML. We retrospectively...
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