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Article

Assessing the influence of CYP2C9 and CYP2C19 genotypes on the metabolism of CBD-cannabis after controlled single and repetitive consumption.

International journal of legal medicine - 1 May 2026

Schulte Janine, Potzel Leila, Frei Priska, Seibert Isabell, Gerlach Kathrin, Mercer-Chalmers-Bender Katja, Scheurer Eva, Schwabedissen Henriette E Meyer Zu, Schulz Iris

Abstract excerpt

The availability of cannabis for recreational and medical purposes has increased substantially, making it the most widely used drug globally and the most frequently detected substance in road traffic controls. Genetic variations in cannabinoid-metabolizing enzymes are relevant but still understudied, and their effects on whole blood concentrations of tetrahydrocannabinol (THC), cannabidiol (CBD), and their...

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Identifiers

PMID: 41553479
DOI: 10.1007/s00414-025-03708-7
PMCID: PMC13161248

Genes

CYP2C9
CYP2C19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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