Article

Predicted Net Effects of Drug-Gene Interactions on Levels of Tetrahydrocannabinol and Cannabidiol

2024-08-07

Abstract excerpt

<title>Abstract</title> <p>Background: Circulating levels of THC and CBD may be altered when administered with medications that strongly or moderately inhibit or induce CYP450 enzymes responsible for metabolizing both substances. THC and CBD levels can also theoretically be altered in individuals who carry germline genetic variants or atypical phenotypes of CYP450 enzymes. In individuals where drug and gene inter...

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Literature Corpus work: bf60c83d-e668-5c07-b8ae-99d43573990e
DOI: 10.21203/rs.3.rs-4731545/v1

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