Article
Dynamic monitoring of circulating tumor DNA in non-Hodgkin lymphoma.
Blood - 23 Jun 2016
Roschewski Mark, Staudt Louis M, Wilson Wyndham H
Abstract excerpt
Response assessment in lymphoma relies on imaging scans that do not capture biologic processes at the molecular level. Monitoring circulating tumor DNA (ctDNA) with next-generation sequencing-based assays can detect recurrent disease prior to scans and "liquid biopsies" for somatic mutations address tumor heterogeneity, clonal evolution, and mechanisms of resistance to guide precision treatment. Preanalytic...
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