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Article

Potassium ion homeostasis modulates mitochondrial function.

The Journal of cell biology - 6 Apr 2026

Waite Adam James, Rao Beiduo, Schinski Elizabeth, Thayer Nathaniel H, Hotz Manuel, Lefebvre Austin E Y T, Sandoval Celeste, Gottschling Daniel E

Abstract excerpt

Age-associated decline in mitochondrial membrane potential (MMP) is a ubiquitous aspect of eukaryotic organisms and is associated with many aging-related diseases. However, it is not clear whether this decline is a cause or consequence of aging, and therefore whether interventions to reduce MMP decline are a viable strategy to promote healthier aging and longer lifespans. We developed a screening platform in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41528311
DOI: 10.1083/jcb.202505110
PMCID: PMC12798708

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