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Article

Serum cystatin C as a biomarker for diabetic retinopathy and its role in diabetic retinopathy-diabetic kidney disease comorbidity.

Journal of translational medicine - 12 Jan 2026

Chen Xiaosi, Yuan Weichen, Zeng Yiyun, Wu Hanyu, Pi Linghui, Yang Yang, Gu Xinming, Zhang Xinyuan

Abstract excerpt

BACKGROUND: To investigate whether serum cystatin C (CysC) can serve as a biomarker for diabetic retinopathy (DR), and explore the comorbidity between DR and diabetic kidney disease (DKD). METHODS: This study used a nested case-control design with Mendelian randomization (MR) analysis. A total of 128 type 2 diabetic patients were categorized into no DR (DM), non-proliferative DR (NPDR), and proliferative DR (PDR)...

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Identifiers

PMID: 41527091
DOI: 10.1186/s12967-025-07552-6
PMCID: PMC12888239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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