Article
Phenotypic age acceleration and omega-6/omega-3 PUFA ratio in dynamic atrial fibrillation-heart failure transitions: a multistate analysis.
The journal of nutrition, health & aging - 1 Feb 2026
Zhang Xianlin, Tang Wenbo, Kang Pinfang, Tang Bi, Du Zhongyan, Cheng Wenke
Abstract excerpt
BACKGROUND: Biological aging and dietary fatty acid balance may influence the bidirectional progression between atrial fibrillation (AF) and heart failure (HF); however, most studies focus on single endpoints, overlooking intermediate states. OBJECTIVE: To evaluate the independent and joint associations of phenotypic age acceleration (PhenoAgeAccel) and the plasma omega-6/omega-3 (ω-6/ω-3) polyunsaturated fatty...
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