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Article

The influence of accelerated aging-related cardiac remodeling on cardiovascular outcomes: an observational study.

The journals of gerontology. Series A, Biological sciences and medical sciences - 7 May 2026

Lv Zhi, Li Kexin, Liu Chang, Liu Peiqi, Kou Zi, Zhang Mingjuan, Gao Dengfeng

Abstract excerpt

BACKGROUND: This study aimed to investigate the associations between phenotypic age acceleration (PhenoAgeAccel) and different CVD outcomes and mortality, examine its relationship with cardiac structure and function using cardiac magnetic resonance imaging (CMR), and explore potential mediating pathways involving cardiac remodeling and cardiometabolic diseases. METHODS: PhenoAgeAccel was defined as the residual...

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PMID: 42054588
DOI: 10.1093/gerona/glag098

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