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Interaction of serum zinc and copper status with fatty acid desaturases on incidence of type 2 diabetes in the EPIC-Potsdam study.

Redox biology - 1 Mar 2026

Prada Marcela, Bezuhla Olha, Kuxhaus Olga, Eichelmann Fabian, Jäger Susanne, Kipp Anna P, Haase Hajo, Schwerdtle Tanja, Schulze Matthias B

Abstract excerpt

AIMS: To examine whether zinc (Zn) and copper (Cu) status influence the association of estimated delta-5 desaturase (D5D), delta-6 desaturase (D6D), and stearoyl-CoA desaturase-1 (SCD1) activities with type 2 diabetes (T2D) risk. METHODS: We used a nested case-cohort design within the EPIC-Potsdam Study (n = 1979; 447 incident T2D cases). Desaturase activities were estimated using erythrocyte fatty acids (FA):...

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Identifiers

PMID: 41518846
DOI: 10.1016/j.redox.2025.103998
PMCID: PMC12818309

Genes

SLC30A8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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