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Article

Recent insights into the relation of Δ5 desaturase and Δ6 desaturase activity to the development of type 2 diabetes.

Current opinion in lipidology - 1 Feb 2012

Kröger Janine, Schulze Matthias B

Abstract excerpt

PURPOSE OF REVIEW: The Δ5 desaturase (D5D) and Δ6 desaturase (D6D) are key enzymes in the metabolism of polyunsaturated fatty acids. This review aims to summarize recent advances towards understanding the relation of the activities of D5D and D6D to the development of type 2 diabetes. RECENT FINDINGS: Prospective studies that investigated fatty acid product-to-precursor ratios in blood as estimates of desaturase...

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Share to Delta-5 Fatty Acid Desaturase
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Share to Stearoyl-CoA Desaturase

Source

Identifiers

PMID: 22123669
DOI: 10.1097/MOL.0b013e32834d2dc5

Genes

FADS1
FADS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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