Article
A scalable high-throughput targeted next-generation sequencing assay for comprehensive genomic profiling of solid tumors.
PloS one - 1 Jan 2021
Conroy Jeffrey M, Pabla Sarabjot, Glenn Sean T, Seager R J, Van Roey Erik, Gao Shuang, Burgher Blake, Andreas Jonathan, Giamo Vincent, Mallon Melissa, Lee Yong Hee, DePietro Paul, Nesline Mary, Wang Yirong, Lenzo Felicia L, Klein Roger, Zhang Shengle
Abstract excerpt
Timely and accurate identification of molecular alterations in solid tumors is essential for proper management of patients with advanced cancers. This has created a need for rapid, scalable comprehensive genomic profiling (CGP) systems that detect an increasing number of therapeutically-relevant variant types and molecular signatures. In this study, we assessed the analytical performance of the TruSight Oncology...
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