Article
A mechanism for telomere-specific telomere length regulation.
Nucleic acids research - 5 Jan 2026
Teplitz Gabriela M, Pasquier Emeline, Bonnell Erin, De Laurentiis Evelina, Bartle Louise, Lucier Jean-François, St-Laurent Gabriel, Dawson Dean S, Wellinger Raymund J
Abstract excerpt
Telomere length is a critical determinant of telomere function and hence chromosome stability. Critically short telomeres induce cellular senescence and division arrest, which eventually may lead to devastating age-related degenerative diseases. Conversely, maintenance of telomere length is a hallmark of cancer. How telomere set-length is established and molecular mechanisms for telomere-specific length...
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