[BCR::ABL-Negative Triple Negative Myeloproliferative Neoplasm --Review].

Abstract excerpt

Triple-negative myeloproliferative neoplasms (TN-MPN) are diseases characterized by absence of the three driver mutations in JAK2, CALR, or MPL, but still exhibit histological and phenotypic features sufficient to diagnose myeloproliferative neoplasms (MPN). Approximately 10% to 20% of essential thrombocythemia (ET) and 5% to 10% of primary myelofibrosis (PMF) cases are reported to be triple negative. TN-MPN may...

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• CALR gene
• CBL gene
• MPL gene
• SF3B1 gene
• SRSF2 gene
• Janus Kinase 2