Article
Development and validation of exhaled breath condensate microRNAs to identify and endotype asthma in children.
PloS one - 1 Jan 2019
Mendes Francisca Castro, Paciência Inês, Ferreira António Carlos, Martins Carla, Rufo João Cavaleiro, Silva Diana, Cunha Pedro, Farraia Mariana, Moreira Pedro, Delgado Luís, Soares Miguel Luz, Moreira André
Abstract excerpt
Detection and quantification of microRNAs (miRNAs) in exhaled breath condensate (EBC) has been poorly explored. Therefore we aimed to assess miRNAs in EBC as potential biomarkers to diagnose and endotype asthma in school aged children. In a cross sectional, nested case control study, all the asthmatic children (n = 71) and a random sample of controls (n = 115), aged 7 to 12 years, attending 71 classrooms from 20...
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