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Article

IL17-related gene polymorphisms associated with orbital inflammatory diseases and their clinical features.

Experimental eye research - 1 Mar 2026

Chen Ding-Ping, Lin Wei-Tzu, Hsu Fang-Ping, Chu Yen-Chang

Abstract excerpt

Autoimmune-associated orbital inflammation refers to the inflammation of orbital tissues resulting from immune system dysregulation. Interleukin-17 (IL-17) plays a critical role in immune defense, tissue repair, inflammation, and tumor progression. Given its immunomodulatory functions, this study aimed to investigate whether single-nucleotide polymorphisms (SNPs) in IL17-related genes contribute to susceptibility...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41490611
DOI: 10.1016/j.exer.2025.110838

Genes

IL17A
IL17F
IL17RA
IL17RC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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