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Article

Sputum Eosinophils Predict Annual Remission of the Frequent Exacerbator Phenotype in COPD: A Prospective Cohort Study.

Lung - 3 Jan 2026

Huang Hailun, Hu Yuling, Gong Zhaoqian, Wang Junrao, Chen Meijia, Yang Liyu, Lan Yisheng, Ouyang Wenshan, Zhao Wenqu, Zhao Haijin

Abstract excerpt

INTRODUCTION: The frequent-exacerbator (FE) phenotype guides COPD management, yet its year-to-year stability and the role of airway eosinophilia in FE remission are uncertain. METHODS: In a single-center prospective cohort (n = 289), patients were classified as FE (≥ 2 moderate or ≥ 1 severe exacerbation in the prior year; n = 88) or non-FE (n = 201) and followed 12 months. FE patients were labeled FE-persistent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41483406
DOI: 10.1007/s00408-025-00867-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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