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Article

Unraveling Key Regulatory Pathways in Non-HCV-Induced Hepatocellular Carcinoma: Insights from Exclusively Mutated Genes and Prognostic Biomarkers.

Asian Pacific journal of cancer prevention : APJCP - 1 Dec 2025

Khalifa Mohamed Kamal, Hmed Ahmed A, Elfeky Khaled S, Bakry Sayed, Elhamshary Manal Osama, Sofy Ahmed R

Abstract excerpt

BACKGROUND: The molecular pathogenesis of hepatocellular carcinoma (HCC) exhibits striking etiological heterogeneity, with non-HCV-associated cases representing an increasingly prominent clinical challenge in regions like Egypt, where environmental carcinogens significantly contribute to the disease burden. METHODS: Through integrated analysis of genomic data Egyptian cohort comprising 48 HCC cases (23 non-HCV,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41459874
DOI: 10.31557/APJCP.2025.26.12.4593
PMCID: PMC13245269

Genes

FGFR1
MET
ERBB2
FLT3

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