Article
Signaling pathways in hepatocellular carcinoma.
Advances in cancer research - 1 Jan 2021
Garcia-Lezana Teresa, Lopez-Canovas Juan Luis, Villanueva Augusto
Abstract excerpt
Despite the recent introduction of new effective systemic agents, the survival of patients with hepatocellular carcinoma (HCC) at advanced stages remains dismal. This underscores the need for new therapies, which has spurred extensive research on the identification of the main drivers of pathway de-regulation as a source of novel therapeutic targets. Frequently altered pathways in HCC involve growth factor...
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