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Prevalence of germline 113 cancer genes in healthy Indonesian hospital staff.

Genes & genomics - 1 Mar 2026

Hayati Mega, Saputra Fahreza, Hayuanta Hubertus Hosti, Setiawan Lyana, Utomo Ahmad Rusdan H

Abstract excerpt

BACKGROUND: The absence of population-specific genetic variant frequency data in Indonesia complicates the interpretation of germline genetic variants of DNA repair genes critical for cancer predisposition. OBJECTIVE: to estimate baseline frequency of pathogenic/likely pathogenic germline variants (P/LP) and variant of unknown significance (VUS), we conducted an exploratory genetic screening in a convenience...

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Identifiers

PMID: 41455088
DOI: 10.1007/s13258-025-01726-8

Genes

FH
BRCA1
BRCA2
CHEK2
FANCA
BRIP1
FANCC
MUTYH
RAD51D
XPA
XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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